Comparing options · Updated October 5, 2026
Ketamine vs. Spravato: What's Different
IV ketamine and Spravato (esketamine) get lumped together, but they differ on FDA status, insurance coverage, cost, and how you receive them.
Safety · Updated October 5, 2026
At-Home Ketamine Therapy: What You're Signing Up For
At-home ketamine costs a fraction of clinic treatment. How the model works, what the FDA has warned about, and how to judge whether a program is responsible.
Logistics · Updated October 12, 2026
How Many Ketamine Treatments Do You Need?
Typical induction schedules for IV ketamine and Spravato, how long results tend to last, what maintenance looks like, and when it's reasonable to stop.
Evidence · Updated October 12, 2026
How Well Does Ketamine Work? The Research, Plainly
What response rates in ketamine and esketamine studies really mean, how long benefits last without maintenance, and what non-response tells you.
Comparing options · Updated October 5, 2026
Ketamine vs. TMS for Treatment-Resistant Depression
Two different paths after antidepressants fail: how ketamine and TMS compare on speed, insurance coverage, side effects, time commitment, and durability.
Comparing options · Updated October 12, 2026
If Ketamine Didn't Work: What Comes Next
How to tell whether ketamine failed, what to ask your prescriber, and what the research says about Spravato, TMS, ECT, medication changes, and therapy.